The blast took place on Saturday when a bomber detonated his explosives on Istiklal Caddesi street in Istanbul’s Beyoglu district.
The street, which adjoins Taksim Square, is also home to cafes, restaurants, and foreign consulate buildings.
Istanbul’s governor Vasip Şahin said that the death toll for the attack has so far reached four. At least 20 people have also been injured in the incident.
According to Turkey’s Dogan news agency, ambulances rushed to the scene of the blast.
Reports say the attacker is among those killed.
The incident comes just days after a bombing attack, claimed by a Kurdish militant group, left about 35 people dead in the capital, Ankara.
Turkey has witnessed at least five major bombing attacks since last July, when it launched a military campaign against militants of the Kurdistan Workers’ Party (PKK) in the southeastern border areas.
The Turkish military has also been conducting offensive operations against the positions of the group in northern Iraq.
The operations began in the wake of a deadly July 2015 bombing in the southern Turkish town of Suruc. More than 30 people died in the attack, which the Turkish government blamed on the Daesh Takfiri terrorist group.
After the bombing, the PKK militants, who accuse the government in Ankara of supporting Daesh, engaged in a series of attacks against Turkish police and security forces.
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