"An Israeli plane hit a car inside the town of Hader, killing two men 5 popular committee forces in the town," said Rami Abdel Rahman, director of the Syrian Observatory for Human Rights.
Hader is a Druze village that lies along the ceasefire line, with the Israeli-occupied portion of the Golan Heights plateau to the west, and the border with Damascus province to the northeast.
According to Hezbollah's official television station Al-Manar, "two members of Syria's National Defence Forces were killed when an Israeli drone targeted their car at the entrance of Hader, in Quneitra province."
The National Defence Forces has fighters operating throughout Syria.
Rebel fighters surrounded the village of Hader on June 17 after fierce clashes with Syria's National Defence Forces in the area.
Druze minority has expressed concern that their brethren in Syria would be targeted by rebels.
According to AFP the Druze are a offshoot of Shiite Islam. Officials say there are 110,000 of them in northern Israel and another 20,000 in the Israeli-occupied Golan.
Israel seized 1,200 square kilometres of the Golan Heights from neighboring Syria in the 1967 Six Day War.