"I do not foresee a scenario in which boots on the ground in Syria, American boots on the ground, would not only be good for America but also would be good for Syria," Obama said during a Friday news conference in the Costa Rican capital, San Jose.
Obama also noted that Arab leaders of the region also agree with his idea that the US shouldn't send ground forces to Syria in a bid to avoid unintended consequences.
"When we rush into things, when we leap before we look, not only do we pay a price but oftentimes we see unintended consequences on the ground," Obama said.
Obama went on to say that his administration will continue to increase pressure on Syria while investigating allegations that the government has used chemical weapons, repeating that it would be a "game-changer." "We will stay on this," Obama said.
"When it comes to using chemical weapons, the entire world should be concerned," he said.
The US president also declined to say what action Washington might take in Syria.
US Defense Secretary Chuck Hagel, however, said on Thursday that Washington is evaluating whether to arm the militants in Syria.
"Arming the rebels - that's an option," he told reporters.
"You look at and rethink all options. It doesn't mean you do or you will. These are options that must be considered with the international community," Hagel said.
On the same day, fresh evidence has shed light on the role of foreign countries, the US in particular, in providing training and assistance to the armed groups and al-Qaeda terrorists in Syria.
In an interview with the state-run BBC, an unnamed senior commander from the terrorist Free Syrian Army (FSA) said the US has been secretly training the insurgents and the al-Qaeda operatives in neighboring Jordan.
"Most of the rebels have some education; it was not hard for them to detect the American accent of the trainer. He spoke through a translator. But the way he spoke indicated that he was American," he explained.
The unrest in Syria began in March 2011, and many people, including large numbers of army and security personnel, have been killed in the violence.
The Syrian government says that the chaos is being orchestrated from outside the country, and there are reports that a very large number of the militants are foreign nationals.
Damascus says the West and its regional allies, including Qatar, Saudi Arabia, and Turkey are supporting the armed groups.
In addition, several international human rights organizations have accused the armed groups fighting in Syria of committing war crimes.