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One of those injured on Monday was in critical condition, authorities said.

US media were reporting that the person who was killed in the incident was the gunman; Press TV reported.

The university put the campus on lockdown and sent a statement on Twitter urging students to shelter in place.

"Buckeye Alert: Active Shooter on campus. Run Hide Fight. Watts Hall. 19th and College," OSU Emergency Management tweeted Monday morning.

The university followed up with another tweet. "Continue to shelter in place in north campus area. Follow directions of Police on scene." 

The university, located in Columbus with 60,000 students, is one of the largest colleges in the US.

Police said it needed time to secure the sprawling campus. Officers were searching the university and were seen escorting people off the campus.

University authorities urged anyone with information about the shooting to call police.

The Bureau of Alcohol,Tobacco, Firearms and Explosives is on the ground in Columbus to assist local authorities with the investigation.

A black bag wrapped with masking tape was found in some bushes.

According to the Gun Violence Archive, more than 13,400 people have been killed as a result of over 52,000 gun-related incidents across the US this year.