Girls and women reported missing by families who are “feared to have travelled to Syria" shot up to 56 during 2015.
Figures released in July showed 43 females are thought to have fled to join the terror group during 2014.
It is feared all women who travel to Syria “will probably never be able to return home.”
Police spokeswoman Helen Ball said: "We are deeply concerned about the numbers of girls, young women and also families who are taking the decision to go to Syria, unaware of the dangers they face when they arrive and the fact that they are unlikely to ever be able to return home to their devastated wider families.
"The personal accounts of the women in this film highlight the harsh reality of life for women and children living in a war torn country.
"I hope they will go some way to helping young women and mothers stop and think about the huge mistake they would be making if they travel."
The statistics were revealed as a short film was released featuring three female Syrian refugees talking about the harsh realities of life in their home country.
The women have also written open letters urging British mothers to take steps to prevent their daughters travelling to the war-zone.
Last February three London schoolgirls – Shamima Begum and Amira Abase, both 15, and Kadiza Sultana, 16 – left for Syria.
Assistant Chief Constable Angela Williams said: "It is important for everyone do everything they can to help stop people from travelling to Syria and other conflict zones.
"Children have been taken to dangerous places and are at great risk; vulnerable people have been brainwashed into travelling.
"My message to mothers across the region is to please come forward if you have any concerns about your loved ones who may be considering travel to Syria.",Express reported.
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