Without citing its sources, Anatolia said that among those wounded was Nurettin Demirtas, the brother of the leader of pro-Kurdish Peoples' Democratic Party (HDP), Selahattin Demirtas.
Ankara has launched a two-pronged "anti-terror" offensive against Islamic State in Iraq and the Levant (ISIL) terrorists in Syria and Kurdistan Workers Party (PKK) militants after a wave of attacks inside the country. But so far the bombardments have focused far more on the Kurdish rebels.
In the latest air strikes on Friday, 28 Turkish F-16s destroyed 65 targets of the PKK including shelters and arms depots, it said.
The heaviest air strikes were on Thursday, when 80 Turkish aircraft hit 100 targets of the PKK, Anatolia said.
"Up until now 260 terrorists have been rendered ineffective (killed) and 380-400 terrorists have been identified as injured, including the brother of Selahattin Demirtas, Nurettin Demirtas," Anatolia said. The air strikes are expected to continue, it added.
The Turkish government has so far refused to officially disclose casualty figures, with one official telling AFP that "this is not a soccer game".
But the sheer number of planes involved in the daily strikes on the PKK targets in northern Iraq has given an idea of the scale of the operation and raised concern in some Western capitals.
German Foreign Minister Frank-Walter Steinmeier on Friday urged Turkey not to "tear down the bridges" that had been built over the last years with its Kurdish minority.
The PKK's insurgency for greater rights and powers for Turkey's Kurdish minority, begun more than 30 years ago, has left tens of thousands dead. The current violence has shattered a ceasefire declared in 2013.