According to reports two militants attacked Abu Khaled al-Suri’s compound on Sunday, and killed him by blowing explosives near the building.
Suri was the representative of al-Qaeda leader Ayman al-Zawahri in Syria and also a co-founder of the al-Qaeda affiliated group of Ahrar al-Sham.
The al-Qaeda-linked Islamic State of Iraq and the Levant (ISIL) is suspected to be behind the attack, reports added.
ISIL has been trying to seize control of the areas in northern Syria.
On February 21, another incident of infighting took place between ISIL members and the so-called Free Syrian Army (FSA) near Bab al-Salameh, north of Aleppo.
The clashes broke out after a car bomb ripped through a crowded refugee camp, killing several people and injuring scores more.
SHI/SHI