In an interview with Lebanese newspaper of al-Akhbar, Asssad highlighted the deepened division among the foreign-backed militant groups, saying that such differences will not bring any fruitful results for rebel groups in Geneva 2 talks.
Assad has stressed the continuation of resistance in occupied Golan Heights till the release all captured areas.
He said if Syrian security forces fail to resist against sectarian rifts raised by militant groups in the region, all Islamic nations will face such threats in near future.
Syrian peace talks scheduled to take place in Geneva next month may be postponed until later in the summer, but organizers remain "optimistic" about their outcome.
Earlier the so-called Syrian National Coalition leader George Sabra appeared to rule out talks in response to heavy rebel losses in the city of Qusayr.
With events on the battlefield turning in favor of Syrian government, there will be less pressure on Assad to join talks.
A bigger setback for the US and its allies in the region is the great success of Syrian troops to regain control of previously captured cities including Qusayr.