Syrian state media cited a military source saying ISIS militants had been killed and their weapons destroyed at the town of al-Sukhna, some 50 km (30 miles) northeast of the ancient city of Palmyra.
The town is also located some 50 km (30 miles) from the provincial boundary of Deir al-Zor province, ISIS' last major foothold in Syria and a major target for the Syrian government.
The terrorists have lost swathes of Syrian territory to separate campaigns being waged by government forces backed by Russia and Iran, and by the U.S.-backed Syrian Democratic (SDF) Forces, which is dominated by the Kurdish YPG militia. The SDF is currently focused on capturing Raqqa city from ISIS.
Syrian government forces advancing from the west have recently crossed into Deir al-Zor province from southern areas of Raqqa province.
ISIS controls nearly all of Deir al-Zor province, which is bordered to the east by Iraq. The Syrian government still controls a pocket of territory in Deir al-Zor city, and a nearby military base.