He was moved to the city of Hit for initial treatment before being transferred to Mosul flanked by security guards, CNN reported.
A spokesman for Iraq's Joint Operations Command confirmed that they had been following Adnani's movements for well over a month before he was injured on Thursday in what is believed to have been a targeted attack.
Adnani is considered the terror network's most prominent public figure in Iraq, having made several audio recordings which have been posted online.
He is held in the same bracket of notoriety as Abu Bakr al-Baghdadi, the so-called caliph of the “Islamic State in Iraq and Syria”, and has been suggested as the next leader should Baghdadi lose his position.
Adnani was held in custody - believed to have been at the American detention facility, Camp Bucca - after being captured by US troops in 2005, remaining a prisoner until 2010.
A £2.5million bounty was issued in May 2014 for information leading to the Syrian born extremist, referring to his 'repeated calls for attacks against Westerns'.
In June of that year, he declared a 'caliphate' for parts of Syria and Iraq indicating ISIS' aim of not just being a terrorist group, but a governing body, According to Daily Mail report.