A group of students outside the college were seemingly the target of the car bomb attack on Wednesday, witnesses said.
The attack took place as several people gathered in front of the building for a police recruitment event, according to security sources.
The people dead and wounded in the incident were taken away by ambulances.
A large plume of smoke also encircled the area of the college.
No group has claimed responsibility for the deadly bomb attack but the al-Qaeda terrorist group in Yemen has carried out similar attacks against the Ansarullah movement in the past.
Last week, over 30 people were killed and dozens of others wounded in an explosion targeting Houthi movement’s Ansarullah fighters in the city of Ibb in central Yemen.