A Palestinian got out of his vehicle near a hitchhiking stop outside the settlement and stabbed three Zionists, killing a female settler, reports asserted.
The Israeli occupation troops shot the Palestinian youth who carried out the operation.
Emergency services spokesman Zaki Heller said a man of about 20 was "very seriously hurt" in the attack outside Hagana station, where footage from the scene showed medics trying to revive a man lying in the road in pools of blood.
One of the paramedics who was first on the scene said his body was covered with stab wounds.
Police spokeswoman Luba Samri said the stabbed man was an Israeli soldier and said the attack was carried out by a Palestinian from the Nablus area in the northern West Bank.
In another context, the Palestinians continued their rallies in the town of Kfar Kanna in Nazareth, clashing with the Zionist occupation troops who killed last Saturday a Palestinian youth.