Israel Premier Benyamin Netanyahu said: "Hamas is responsible and Hamas will pay." Hamas denies any involvement.
Israel launched more than 30 air strikes on the Gaza Strip overnight.
Israeli troops flooded into the Palestinian village of Halhul and the homes of two Hamas men, Marwan Qawasmeh and Amer Abu Aishah, named by Israel as prime suspects, have been blown up.
Hamas says Israel is using a "story" to justify a "war" on Palestinians.
The deaths of the students, who were last seen at a junction near al-Khalil in the West Bank as they hitchhiked home, has sparked international condemnation.
Their bodies were found in a pit near Halhul.
Israeli security forces have set up blockades and closed down whole areas around the town, which is just a few kilometers from where the teenagers were last seen.
Israeli regime also has killed five Palestinians and arrested more than 400 others in search for the trio.
BA/BA