Sawsan Haddad, an engineer in the coastal city of Latakia, submitted her application to the Supreme Constitutional Court on Saturday, becoming the third runner for the presidential vote.
The 51-year-old woman had been a member of the ruling al-Baath party until last year, when she withdrew from the party for undeclared reasons.
Speaking to reporters at the constitutional court, Haddad said that it's about time for women to come forward to participate in top positions in Syria.
She emphasized that she is independent and not part of any party.
The ten-day registration for the top Syrian post started on Tuesday. Aside from Haddad, two lawmakers have so far declared their candidacy to the election.
Voting for Syrians inside the country will start on June 3, while overseas Syrians will cast their votes on May 28.
Several candidates are expected to run for the presidency in accordance with the new constitution. Syria's electoral law stipulates that all applicants must have lived in Syria for 10 consecutive years prior to nomination.
By law each runner for the elections must secure the backing of 35 parliamentarians. The Supreme Constitutional Court, which is tasked with overseeing the presidential elections' process, must study their applications before announcing them candidates within the five days after the ten-day registration time frame.
More than 150,000 people have been reportedly killed and one third of the population displaced in the foreign-hatched clashes between the Syrian army and militant groups.
NTJ/HH