Thick plumes of black smoke blanketed the city's skyline as ambulances rushed to the scene of the blast, the second in the capital in less than a week.
According to Lebanese Health Ministry, four people have been found dead.
Sixty others were wounded in the blast, the ministry announced.
Hundreds of people flooded the site of the explosion, assisting Lebanese Red Cross personnel carry the wounded into ambulances in the densely populated neighborhood.
The car bomb damaged dozens of vehicles parked nearby as well as several buildings in the commercial, residential area.
Minutes after the explosion, gunshots were fired in the air to disperse the crowd.
Hezbollah's Al-Manar television reported that an explosive-rigged four-wheel-drive vehicle was parked on the Al-Areed Street.
SHI/SHI