On Friday, the protesters staged a demonstration in the city of Sa'ada chanting slogans and holding placards against the interference.
They also slammed Washington for launching assassination drone strikes in the country.
The protest followed a drone attack against a wedding convoy on December 12, which left 17 people dead near Rada in the southwestern province of al-Bayda.
Yemeni parliament has banned US assassination drone strikes inside the Arab country to prevent more civilians getting killed.
Washington has stepped up its assassination drone operations in Yemen over the past few years.
The US claims the targets of the drone attacks are al-Qaeda militants, but local officials and witnesses maintain that civilians have been the main victims of the attacks over the past few years.
According to the Washington-based think tank the New America Foundation, US drone attacks in the Arab country almost tripled last year, surging from 18 to 53.
The US has come under fire for increasing its drone attacks in Yemen, where the people have held many demonstrations to condemn the violation of their national sovereignty.
NTJ/SHI