According to an Egyptian judiciary source, among those facing sanctions are Brotherhood general guide Mohammed Badie, his two deputies Khairat al-Shater and Rashad Bayoumi, as well as Salafist leader Hazem Abu Ismail and preacher Safwat Higazi.
Around 15 MB politicians have already had their assets frozen as part of the crackdown on teh group.
The five are currently detained, being accused of inciting the murder of protesters opposed to ousted jailed President Mohamed Morsi.
Egyptian authorities have been cracking down on Muslim Brotherhood members and supporters since the army toppled Morsi on July 3 following mass protests against his rule.
More than 2,000 MB activists have been arrested and most of the Brotherhood's leaders were jailed on charges of inciting or taking part in violence.
Over the same period, more than 1,000 people have been killed in political violence. Most were protesters killed by security forces breaking up pro-Morsi camps in Cairo.
About 100 were members of the security forces.
HV/SHI