In the Mediterranean city of Alexandria, the fierce clashes between rival protesters erupted after Friday prayers over this week’s ouster of Morsi in a military coup, according to Egyptian Health Ministry officials.
Twelve people were killed and at least 200 injured in the Alexandria violence.
In the capital Cairo, security forces shot dead three pro-Morsi demonstrators on Friday outside the headquarters of the Republican Guard that provoked deadly clashes between the protesters and the forces.
Pro- and anti-Morsi protesters also clashed in running street battles in the capital, leaving several more people dead and scores of others injured.
The demonstrators hurled fireworks and stones at each other across a bridge near Cairo’s Tahrir Square.
In separate incidents in the North Sinai town of El Arish, five policemen were shot dead by unidentified gunmen.
In the southern city of Assiut, at least one more person died from gunshot wounds.
The Muslim Brotherhood’s political wing, the Freedom and Justice Party has called on the supporters of Morsi to continue protests against his ouster.
The Tamarod movement, which spearheaded massive demonstrations against Morsi, and opposition groups have also called on Egyptians to hold rallies on Sunday to defend “the legitimacy of the revolution.”