"If the government of (Prime Minister Recep Tayyip) Erdogan calls for a joint, transparent investigation by the two countries, we have no objection, in order to find the truth," Syria’s Information Minister Omran al-Zohbi said.
"The truth must be announced to the Syrian and Turkish people," official media quoted him as saying.
The twin car bombings that rocked the town of Reyhanli in southern Turkey on Saturday killed 51 people and wounded dozens more.
Following the attacks, Turkish protesters poured into the streets, calling on Erdogan to step down. The demonstrators said the outbreak of violence was due to the Erdogan administration’s anti-Syria policy.
Turkey has been one of Syrian President Bashar al-Assad's harshest critics and has supported the foreign-backed militants fighting to topple his government.
Turkish opposition parties have censured the Turkish government for its intervention in Syria’s internal affairs.